Lysozyme chloride, pyridoxine hydrochloride.
Each lozenge contains: Lysozyme Chloride (derived from egg white): 80mg.
Pyridoxine Hydrochloride: 40mg.
Pharmacology: Pharmacodynamics: Lysozyme is an enzyme having a mucopolysaccharide lysing action. It enhances the effect of antibiotics to destroy or weaken cell bacteria.
Lysozyme also accelerates immuno-bacteriolysis and activates the phagocytosis activity of leukocytes to destroy bacteria and viruses.
Lysozyme is widely distributed in tears, nasal discharge, saliva and also breast milk.
Lysozyme extracted from egg-white is used clinically for the intensification of natural defense mechanisms, restoration of damaged tissue and anti-inflammation.
The body needs pyridoxine hydrochloride in order to make cells of the immune system. Pyridoxine hydrochloride helps to improve immune response to the increase in production of antibodies and also helps in communicative interactions between cytokines and chemokines.
Pharmacokinetics: With a single 900mg (potency) oral dose of lysozyme chloride, the peak plasma concentration occurred about 30 minutes to 1 hour after administration.
Pyridoxine hydrochloride is absorbed rapidly from the upper intestine regardless of the size of the dose given.
Absorption may also occur from the ileum and to a small extent from the colon. These observations suggest the possibility that pyridoxine may be absorbed by diffusion.
Pyridoxine is rapidly converted in the liver to pyridoxine phosphate, pyridoxal phosphate and pyridoxamine phosphate via oxidation, this causes the release of pyridoxal and so pyridoxal phosphate to the general circulation where it reaches other organs chiefly as circulating pyridoxal.
In urine, pyridoxine was excreted primarily unchanged with a small amount of only one metabolite, most likely 4-pyridoxic acid.
Oral liquid: Absorption and Distribution: following administration of [1]-labelled egg white lysozyme (2mg/kg) into the intestinal tract of rats, peak serum and lymphatic concentration occurred at 30 minutes.
For the adjunctive treatment of sore throat.
Recommended Dose: Adult: 1 lozenge to be sucked or dissolved in the mouth once or twice daily or according to doctor's prescription.
Route of Administration: For oral use.
Symptoms: Diarrhoea, anorexia, gastric discomfort.
Treatment: Stop administration.
Patients hypersensitive to egg-white. Patients with a history of hypersensitivity to any ingredients of Homecare Noflux Lozenges.
Patients with an allergic predisposition manifested as atopic dermatitis, bronchial asthma, drug allergy or food allergy to egg or pyridoxine hydrochloride (Vitamin B6).
Abuse of pyridoxine may be responsible for sensory neuropathy that occurs with high doses of pyridoxine (> 200mg/day) for a long period of time (months to years). This is usually reversible when the treatment is stopped.
Consult the doctor if condition does not improve after 5 days of treatment.
It is best not to use this medicine during pregnancy and breastfeeding.
May cause diarrhoea, anorexia, stomach discomfort, nausea and vomiting.
May cause hypersensitivity reactions such as skin rashes.
In rare case, shock may occur with administration of this drug. Therefore, patients should be carefully monitored during Homecare Noflux Lozenges.
Store at temperature below 30°C. Protect from light and moisture.
Shelf Life: 2 years from the date of manufacture.
J05AX02 - lysozyme ; Belongs to the class of other antivirals. Used as a direct acting antiviral in the systemic treatment of viral infections.
Homecare Noflux Lozenge loz
50 × 10's
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